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BMC Psychiatry

, 7:39

First Online: 09 August 2007Received: 12 February 2007Accepted: 09 August 2007


BackgroundThe Major Depression Inventory MDI is a new, brief, self-report measure for depression based on the DSM-system, which allows clinicians to assess the presence of a depressive disorder according to the DSM-IV, but also to assess the severity of the depressive symptoms.

MethodsWe examined the sensitivity, specificity, and psychometric qualities of the MDI in a consecutive sample of 258 psychiatric outpatients. Of these patients, 120 had a mood disorder 70 major depression, 49 dysthymia. A total of 139 subjects had a comorbid axis-I diagnosis, and 91 subjects had a comorbid personality disorder.

ResultsCrohnbach-s alpha of the MDI was a satisfactory 0.89, and the correlation between the MDI and the depression subscale of the SCL-90 was 0.79 p < .001. Subjects with major depressive disorder MDD had a significantly higher MDI score than subjects with anxiety disorders but no MDD, dysthymias, bipolar, psychotic, other neurotic disorders, and subjects with relational problems. In ROC analysis we found that the area under the curve was 0.68 for the MDI. A good cut-off point for the MDI seems to be 26, with a sensitivity of 0.66, and a specificity of 0.63. The indication of the presence of MDD based on the MDI had a moderate agreement with the diagnosis made by a psychiatrist kappa: 0.26.

ConclusionThe MDI is an attractive, brief depression inventory, which seems to be a reliable tool for assessing depression in psychiatric outpatients.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-244X-7-39 contains supplementary material, which is available to authorized users.

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Autor: Pim Cuijpers - Jack Dekker - Annemieke Noteboom - Niels Smits - Jaap Peen


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