Quantitative EEG findings in patients with acute, brief depression combined with other fluctuating psychiatric symptoms: a controlled study from an acute psychiatric departmentReportar como inadecuado




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BMC Psychiatry

, 8:89

First Online: 11 November 2008Received: 06 June 2008Accepted: 11 November 2008

Abstract

BackgroundPatients with brief depressive episodes and concurrent rapidly fluctuating psychiatric symptoms do not fit current diagnostic criteria and they can be difficult to diagnose and treat in an acute psychiatric setting. We wanted to study whether these patients had signs of more epileptic or organic brain dysfunction than patients with depression without additional symptomatology.

MethodsSixteen acutely admitted patients diagnosed with a brief depressive episode as well as another concurrent psychiatric diagnosis were included. Sixteen patients with major depression served as controls. Three electroencephalographic studies EEG were visually interpreted and the background activity was also analysed with quantitative electroencephalography QEEG.

ResultsThe group with brief depression and concurrent symptoms had multiple abnormal features in their standard EEG compared to patients with major depression, but they did not show significantly more epileptiform activity. They also had significantly higher temporal QEEG delta amplitude and interhemispheric temporal delta asymmetry.

ConclusionOrganic brain dysfunction may be involved in the pathogenesis of patients with brief depressive episodes mixed with rapidly fluctuating psychiatric symptoms. This subgroup of depressed patients should be investigated further in order to clarify the pathophysiology and to establish the optimal evaluation scheme and treatment in an acute psychiatric setting.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-244X-8-89 contains supplementary material, which is available to authorized users.

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Autor: Marte Helene Bjørk - Trond Sand - Geir Bråthen - Olav M Linaker - Gunnar Morken - Brigt M Nilsen - Arne Einar Vaaler

Fuente: https://link.springer.com/







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