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Clinical Practice and Epidemiology in Mental Health

, 4:26

First Online: 17 November 2008Received: 25 February 2008Accepted: 17 November 2008


Background and objectiveAsperger-s Syndrome AS is a pervasive developmental disorder that is sometimes unrecognized, especially in the adult psychiatric setting. On the other hand, in patients with an AS diagnosis, comorbid psychiatric disorders may be unrecognized in the juvenile setting. The aim of the paper is to show and discuss some troublesome and complex problems of the management of patients with AS and comorbid Bipolar Disorder BD.

MethodsThe paper describes three patients affected by AS and bipolar spectrum disorders.

Results and conclusionMood stabilizers and 2 generation antipsychotics were effective in the treatment of these AS patients with comorbid BD, while the use of antidepressants was associated with worsening of the mood disorder.

It is of importance to recognize both the psychiatric diagnoses in order to arrange an exhaustive therapeutic program and to define specific and realistic goals of treatment.

AbbreviationsADHDAttention Deficit Hyperactivity Disorder

ASAsperger Syndrome

BDBipolar Disorder

OCDObsessive-Compulsive Disorder

PDDPervasive Developmental Disorders

SSRISelective Serotonin Reuptake Inhibitors

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Autor: Michele Raja - Antonella Azzoni


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