Comparison of temporal changes in psychological distress after hematopoietic stem cell transplantation among the underlying diseases of Japanese adult patientsReportar como inadecuado




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BioPsychoSocial Medicine

, 2:24

First Online: 21 November 2008Received: 27 August 2008Accepted: 21 November 2008

Abstract

BackgroundAlthough hematopoietic stem cell transplantation HSCT can potentially cure some hematological malignancies, patients who undergo HSCT experience psychological distress. However, there have been few studies on the short-term influence of HSCT on psychological distress.

MethodsThe subjects were 71 patients with hematological malignancies who underwent HSCT: 33 with acute leukemia, 19 with chronic leukemia, nine with myelodysplastic syndrome, and 10 with malignant lymphoma. Psychological distress was assessed prior to HSCT and on the seventh day after HSCT using the Profile of Mood States POMS.

ResultsWith regard to Anger-Hostility, the interaction of time pre- and post-HSCT and group the four groups was significant in male patients p = 0.04, but not in female patients. With regard to the other subscales of POMS, there was no significant main effect or interaction in male or female patients.

ConclusionIt may be important to provide psychological support to patients throughout the period of HSCT in consideration of differences in mood changes associated with the underlying disease and patient sex in order to provide efficient psychiatric intervention for both better psychiatric and survival outcomes.

Electronic supplementary materialThe online version of this article doi:10.1186-1751-0759-2-24 contains supplementary material, which is available to authorized users.

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Autor: Wataru Fukuo - Kazuhiro Yoshiuchi - Yoshiyuki Takimoto - Noriyuki Sakamoto - Hiroe Kikuchi - Maki Hachizuka - Shuji Inada -

Fuente: https://link.springer.com/







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