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BioPsychoSocial Medicine

, 4:9

First Online: 23 August 2010Received: 29 January 2010Accepted: 23 August 2010


BackgroundSince the 1980s, a high EEG abnormality rate has been reported for patients with panic disorder. However, how the EEG abnormalities of panic disorder patients are related to the clinical features and pathology of these patients has yet to be clarified. In this study we investigated whether or not EEG abnormalities are related to the 13 symptoms in the DSM-IV criteria for a diagnosis of panic attacks.

MethodsSubjects were 70 patients diagnosed with panic disorder.

Logistic regression analysis was performed with EEG findings as dependent variables and age, sex and with or without the 13 symptoms as independent variables.

Results1EEG findings for panic disorder patients with EEG abnormalities: Of the 17 patients, 13 had repeated slow waves in the θ-band; the most prevalent EEG abnormality found in this study. Paroxysmal abnormality interpreted as epileptiform was found in only two cases. 2Nausea or abdominal distress 37.7% vs 82.45%, OR-12.5, derealization or depersonalization 7.5% vs 47.1%, OR = 13.9, and paresthesias 43.4% vs 64.7%, OR = 7.9, were extracted by multivariate analysis as factors related to EEG abnormalities.

ConclusionOf the 70 patients studied, 17 had EEG abnormalities. Among these 17 cases -repeated slow waves in the θ-band- was the most common abnormality. The factors identified as being related to EEG abnormalities are nausea or abdominal distress, derealization or depersonalization, and paresthesias. The study indicated that physiological predispositions are closely related to panic attacks.

Electronic supplementary materialThe online version of this article doi:10.1186-1751-0759-4-9 contains supplementary material, which is available to authorized users.

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Autor: Karin Hayashi - Mariko Makino - Masahiro Hashizume - Koichi Nakano - Koji Tsuboi

Fuente: https://link.springer.com/

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