Fever of Unknown Origin in a Patient with Confirmed West Nile Virus MeningoencephalitisReport as inadecuate

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Case Reports in Infectious Diseases - Volume 2014 2014, Article ID 120709, 3 pages -

Case Report

Universidad Autónoma de Guadalajara, Av Patria 1201, Lomas del Valle, 45129 Zapopan, JAl, Mexico

Scottsdale Healthcare Shea Medical Center, 9003 E. Shea Boulevard, Scottsdale, AZ 85260, USA

Received 10 July 2014; Revised 25 November 2014; Accepted 27 November 2014; Published 14 December 2014

Academic Editor: Gernot Walder

Copyright © 2014 Alexander Sabre and Laurie Farricielli. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


West Nile Virus WNV, an RNA arbovirus and member of the Japanese encephalitis virus antigenic complex, causes a wide range of clinical symptoms, from asymptomatic to encephalitis and meningitis. Nearly all human infections of WNV are due to mosquito bites with birds being the primary amplifying hosts. Advanced age is the most important risk factor for neurological disease leading most often to poor prognosis in those afflicted. We report a case of WNV meningoencephalitis in a 93-year-old Caucasian male who presented with fever of unknown origin FUO and nuchal rigidity that rapidly decompensated within 24 h to a persistent altered mental state during inpatient stay. The patient’s ELISA antibody titers confirmed pathogenesis of disease by WNV; he given supportive measures and advanced to an excellent recovery. In regard to the approach of FUO, it is important to remain impartial yet insightful to all elements when determining pathogenesis in atypical presentation.

Author: Alexander Sabre and Laurie Farricielli

Source: https://www.hindawi.com/


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