Tricuspid Valve Regurgitation after Orthotopic Heart Transplantation: Prevalence and EtiologyReportar como inadecuado




Tricuspid Valve Regurgitation after Orthotopic Heart Transplantation: Prevalence and Etiology - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Journal of TransplantationVolume 2012 2012, Article ID 120702, 8 pages

Clinical Study

Heart Transplantation Unit, Department of Cardiac Surgery, Leviev Heart Center, Sheba Medical Center, and the Sackler Faculty of Medicine, Tel Aviv University, 52621 Ramat Gan, Israel

Heart Institute, Leviev Heart Center, Sheba Medical Center, and the Sackler Faculty of Medicine, Tel Aviv University, 52621 Ramat Gan, Israel

Received 12 May 2012; Revised 13 July 2012; Accepted 27 July 2012

Academic Editor: Andreas Zuckermann

Copyright © 2012 Yaniv Berger et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Tricuspid valve regurgitation TR after orthotopic heart transplantation OHT is common. The aims of this study were to determine the prevalence of TR after OHT, to examine the correlation between its development and various variables, and to determine its outcomes. Methods. All 163 OHT patients who were followed up between 1988 and 2009 for a minimal period of 12 months were divided into those with no TR-mild TR and those with at least mild-moderate TR, as assessed by doppler echocardiography. These groups were compared regarding preoperative hemodynamic variables, surgical technique employed, number of endomyocardial biopsies, number of acute cellular rejections, incidence of graft vasculopathy, and clinical outcomes. Results. At the end of the followup average 8.2 years significant TR was evident in 14.1% of the patients. The development of late TR was found by univariate, but not multivariate, analysis to be significantly correlated with the biatrial surgical technique and the presence of graft vasculopathy . TR development was found to be correlated with the need for tricuspid valve surgery but not with an increased mortality. Conclusions. The development of TR after OHT may be related to the biatrial anastomosis technique and to graft vasculopathy.





Autor: Yaniv Berger, Yedael Har Zahav, Yigal Kassif, Alexander Kogan, Rafael Kuperstein, Dov Freimark, and Jacob Lavee

Fuente: https://www.hindawi.com/



DESCARGAR PDF




Documentos relacionados