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Canadian Journal of Infectious Diseases and Medical Microbiology - Volume 24 2013, Issue 3, Pages e53-e56

Original Article

Division of Infectious Diseases, Children’s Hospital of Eastern Ontario, University of Ottawa, Canada

Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, Ontario, Canada



Copyright © 2013 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Methicillin-resistant Staphylococcus aureus MRSA infections were uncommon in children in Canada until the 1990s. Using a standardized case report form, treating physicians reported children hospitalized due to MRSA infections in Canadian hospitals through the Canadian Pediatric Surveillance Program in a 24-month period 2008 to 2010. Of 155 cases reported, 70% were ≤4 years of age and approximately one-third had an underlying medical condition. The most common clinical infections involved skin and soft tissue 69%, the lower respiratory tract 12%, and bone and joint 10%. Almost one-third had had contact with the health care environment in the previous year and 18% had a known household member with MRSA. Initial therapy with a beta-lactam alone occurred in 65%, while 22% included vancomycin. No child in this cohort died but 14% required admission to the intensive care unit. Of 143 reports of individual isolates, 93% were reported susceptible to trimethoprim-sulfamethoxazole, 63% to clindamycin and 50% to mupirocin.

The present study involved only children hospitalized with MRSA infections. It may not be representative of the children treated as outpatients nor children in selected areas of Canada where MRSA infections may be more endemic. Further targeted surveillance to identify risks and treatment practices in these populations may be important.





Autor: Kirk Ryan Leifso, Denise Gravel, Aboubaker Mounchili, Sherif Kaldas, and Nicole Le Saux

Fuente: https://www.hindawi.com/



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