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Journal of NanomaterialsVolume 2012 2012, Article ID 548389, 19 pages

Review Article

Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

State Key Laboratory of New Ceramic and Fine Processing, Tsinghua University, Beijing 100084, China

Received 27 February 2012; Accepted 3 April 2012

Academic Editor: Shuming Zhang

Copyright © 2012 Xiaoming Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In recent years, nanoparticles NPs have increasingly found practical applications in technology, research, and medicine. The small particle size coupled with their unique chemical and physical properties is thought to underline their exploitable biomedical activities. Its form may be latex body, polymer, ceramic particle, metal particles, and the carbon particles. Due to their small size and physical resemblance to physiological molecules such as proteins, NPs possess the capacity to revolutionise medical imaging, diagnostics, therapeutics, as well as carry out functional biological processes. But these features may also underline their toxicity. Indeed, a detailed assessment of the factors that influence the biocompatibility and toxicity of NPs is crucial for the safe and sustainable development of the emerging NPs. Due to the unique structure, size, and shape, much effort has been dedicated to analyzing biomedical applications of nanotubes.This paper focuses on the current understanding of the biocompatibility and toxicity of NPs with an emphasis on nanotubes.

Autor: Xiaoming Li, Lu Wang, Yubo Fan, Qingling Feng, and Fu-zhai Cui



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