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BioMed Research InternationalVolume 2014 2014, Article ID 369509, 7 pages

Research Article

Molecular Imaging and Oncology Group, IDIS Research Institute, Travesía da Choupana s-n, 15706 Santiago de Compostela, Spain

Nuclear Medicine Department, University Hospital of Santiago de Compostela CHUS, Travesía da Choupana s-n, 15706 Santiago de Compostela, Spain

Molecular Imaging Group, Faculty of Medicine, University of Santiago de Compostela USC, 15782 Santiago de Compostela, Spain

Fundacion Tejerina, Calle de José Abascal 40, 28003 Madrid, Spain

Received 4 December 2013; Accepted 23 March 2014; Published 14 May 2014

Academic Editor: Bianca Gutfilen

Copyright © 2014 P. Aguiar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The traditional lack of techniques suitable for in vivo imaging has induced a great interest in molecular imaging for preclinical research. Nevertheless, its use spreads slowly due to the difficulties in justifying the high cost of the current dedicated preclinical scanners. An alternative for lowering the costs is to repurpose old clinical gamma cameras to be used for preclinical imaging. In this paper we assess the performance of a portable device, that is, working coupled to a single-head clinical gamma camera, and we present our preliminary experience in several small animal applications. Our findings, based on phantom experiments and animal studies, provided an image quality, in terms of contrast-noise trade-off, comparable to dedicated preclinical pinhole-based scanners. We feel that our portable device offers an opportunity for recycling the widespread availability of clinical gamma cameras in nuclear medicine departments to be used in small animal SPECT imaging and we hope that it can contribute to spreading the use of preclinical imaging within institutions on tight budgets.





Autor: P. Aguiar, J. Silva-Rodríguez, M. Herranz, and A. Ruibal

Fuente: https://www.hindawi.com/



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