The Drop That Spilled the Cup: Acute Myocardial Infarction in a Young Woman with Underlying Thrombophilic Polymorphisms and Oral Contraceptive UseReportar como inadecuado




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Case Reports in Cardiology - Volume 2014 2014, Article ID 249715, 4 pages -

Case Report

Unit of Cardiovascular Disease, Hospital San Vincenzo, Contrada Sirina, 98039 Taormina, Italy

Cardiac Intensive Care Unit, Hospital San Vincenzo, Contrada Sirina, 98039 Taormina, Italy

Cardiovascular Imaging, Hospital San Vincenzo, Contrada Sirina, 98039 Taormina, Italy

Cardiac Catheterization Lab, Hospital San Vincenzo, Contrada Sirina, 98039 Taormina, Italy

Vita-Salute San Raffaele University, San Raffaele Hospital, 58 Via Olgettina, 20132 Milan, Italy

Received 17 July 2014; Accepted 8 December 2014; Published 23 December 2014

Academic Editor: Yoko Miyasaka

Copyright © 2014 Nunzio Russo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We present the case of a 28-year-old woman who was admitted to our cardiology unit for acute coronary syndrome. Her history was notable for cardiovascular disease familiarity, active smoking, and oral contraceptive use. On further analysis, she was noted to have thrombophilic polymorphisms involving the plasminogen activator inhibitor PAI, angiotensin-converting enzyme ACE, and methylenetetrahydrofolate reductase MTHFR genes. We discuss the implications that these cofactors may have had in the genesis of the disease.





Autor: Nunzio Russo, Enrico Franzì, Gianfranco Capilli, Anella Antonietta Patané, Silvia Paola Russo, and Rosario Evola

Fuente: https://www.hindawi.com/



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