New uses of the Migraine Screen Questionnaire MS-Q: validation in the Primary Care setting and ability to detect hidden migraine. MS-Q in Primary CareReportar como inadecuado

New uses of the Migraine Screen Questionnaire MS-Q: validation in the Primary Care setting and ability to detect hidden migraine. MS-Q in Primary Care - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Neurology

, 10:39

First Online: 08 June 2010Received: 26 February 2010Accepted: 08 June 2010


BackgroundPC plays an important role in early diagnosis of health disorders, particularly migraine, due to the financial impact of this disease for the society and its impact on patients- quality of life. The aim of the study was to validate the self-administered MS-Q questionnaire for detection of hidden migraine in the field of primary care PC, and to explore its use in this setting.

MethodsCross-sectional, observational, and multicentre study in subjects above 18 years of age patients attending PC centers regardless of the reason for consultation. A MS-Q score ≥ 4 was considered possible migraine. Level of agreement with IHS criteria clinical diagnosis kappa coefficient, and instrument-s validity properties: sensitivity, specificity, positive PPV and negative NPV predictive values were determined. The ability of the instrument to identify possible new cases of migraine was calculated, as well as the ratio of hidden disease compared to the ratio obtained by IHS criteria.

ResultsA total of 9,670 patients were included 48.9 ± 17.2 years mean ± SD; 61.9% women, from 410 PC centers representative of the whole national territory. The clinical prevalence of migraine according to the IHS criteria was 24.7%, and 20.4% according to MS-Q: Kappa index of agreement 0.82 p < 0.05. MS-Q sensitivity was 0.82 95% CI, 0.81 - 0.84, specificity 0.97 95% CI, 0.98 - 0.99, PPV 0.95 95% CI, 0.94 - 0.96, and NPV 0.94 95% CI, 0.93 - 0.95. No statistically significant differences were found in the percentages of patients with de novo and hidden migraine identified by MS-Q and by IHS criteria: 5.7% vs. 6.1% and 26.6% vs. 24.1%, respectively.

ConclusionsThe results of the present study confirm the usefulness of the MS-Q questionnaire for the early detection and assessment of migraine in PC settings, and its ability to detect hidden migraine.

AbbreviationsIHSInternational Headache Society

MS-QMigraine Screen Questionnaire

PCPrimary Care

NPVnegative predictive value

PPVpositive predictive value

PPRpositive probability ratio

NPRnegative probability ratio.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2377-10-39 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Autor: Miguel J Láinez - Jesús Castillo - Manuel Domínguez - Gemma Palacios - Silvia Díaz - Javier Rejas


Documentos relacionados