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Journal of Neurology

, Volume 258, Issue 4, pp 596–602

First Online: 24 October 2010Received: 24 June 2010Revised: 18 September 2010Accepted: 07 October 2010


The scientific evidence for weather being a trigger factor for migraine attacks is inconclusive. We investigated the association between weather components and the onset and severity of attacks. Headache diaries of 20 migraineurs were analyzed retrospectively and correlated in 4-h intervals to atmospheric air pressure, temperature, and relative air humidity in Berlin Germany for a period of 12 consecutive months. Absolute values and relative changes within the preceding 24 h were analyzed. Migraine attacks started most frequently at 4 a.m. and reached the highest intensity between 4 and 8 a.m. A highly significant association between meteorological variables and the occurrence of migraine attacks was found in six patients. The onset of an attack as well as high headache intensity was associated with lower temperature and higher humidity. Our data indicate that a subgroup of migraineurs is highly sensitive to changes of certain weather components.

KeywordsMigraine Weather Temperature Humidity Atmospheric pressure P. Martus and U. Reuter contributed equally to the manuscript.

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Author: Jan Hoffmann - Hendra Lo - Lars Neeb - Peter Martus - Uwe Reuter


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