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The Journal of Headache and Pain

, Volume 12, Issue 2, pp 227–233

First Online: 25 March 2011Received: 02 September 2010Accepted: 13 December 2010


The objective of this study was to assess the prevalence of and risk factors for primary headaches in juvenile myoclonic epilepsy JME. Headache was classified in 75 patients with JME using a questionnaire, and its prevalence was correlated with the literature on the general population and clinical data. Headache was present in 47 patients. Thirty-one had migraine 20 migraine without aura MO, 11 migraine with aura MA. Fourteen patients with migraine had tension-type headache TTH in addition. Sixteen had only TTH. Comparison with the general population revealed a significantly higher prevalence of migraine RR 4.4, MO 3.6, MA 7.3 and TTH 3.4 in JME. Risk factors for migraine and MO were female gender and for MA family history of migraine in first-degree relatives. Migraine and MA were associated with fairly controlled generalized tonic clonic seizures, MO with absences. Together with its strong genetic background, JME appears to be an attractive homogenous subtype of epilepsy for genetic research on migraine.

KeywordsJuvenile myoclonic epilepsy Headache Migraine Prevalence  Download fulltext PDF

Autor: Christoph J. Schankin - Jan Rémi - Ira Klaus - Petra Sostak - Veronika M. Reinisch - Soheyl Noachtar - Andreas Straube

Fuente: https://link.springer.com/

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