The Serum IL-6 Profile and Treg-Th17 Peripheral Cell Populations in Patients with Type 1 DiabetesReport as inadecuate




The Serum IL-6 Profile and Treg-Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes - Download this document for free, or read online. Document in PDF available to download.

Mediators of InflammationVolume 2013 2013, Article ID 205284, 7 pages

Research Article

Department of Immunology, Medical University of Gdańsk, Dębinki 1, 80-210 Gdańsk, Poland

Clinic of Pediatrics, Department of Diabetology and Endocrinology, Medical University of Gdańsk, 80-210 Gdańsk, Poland

Received 30 October 2012; Accepted 20 January 2013

Academic Editor: Eric F. Morand

Copyright © 2013 Monika Ryba-Stanisławowska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17, which have contradictory functions in the control of inflammation. The present study provides a quantitative analysis regarding the Th17-Treg cell balance in peripheral blood of children with type 1 diabetes and its association with serum IL-6 level.





Author: Monika Ryba-Stanisławowska, Maria Skrzypkowska, Jolanta Myśliwska, and Małgorzata Myśliwiec

Source: https://www.hindawi.com/



DOWNLOAD PDF




Related documents