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The Journal of Headache and Pain

, Volume 13, Issue 3, pp 243–245

First Online: 17 February 2012Received: 21 November 2011Accepted: 26 January 2012


Late onset aura LOA is usually considered benign but raises diagnostic uncertainties. We compared individuals with LOA >45 years of age at aura onset with those of early onset EOA in clinical features, vascular risk factors and imaging, in a retrospective study design including patients with migraine aura and age >44 years at first visit. In 77 cases 51 EOA and 26 LOA, no differences were found in gender distribution, family or personal history of migraine without aura, type of aura symptoms or imaging findings. LOA patients’ were more likely to not fulfil all ICHD-II aura criteria and to lack headache. This data suggest that LOA and EOA are overall identical but there are differences in presentation that deserve a better characterization by a prospective study.

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Author: Isabel Pavão Martins - Tomás Goucha - Ines Mares - Ana Filipa Antunes


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