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Case Reports in Obstetrics and Gynecology - Volume 2014 2014, Article ID 204915, 4 pages -

Case Report

Department of Obstetrics and Gynecology, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium

Department of Obstetrics and Gynecology, University Hospital KU Leuven Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium

Department of Pathology, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium

Received 8 October 2014; Revised 16 December 2014; Accepted 16 December 2014; Published 31 December 2014

Academic Editor: Erich Cosmi

Copyright © 2014 W. Dendas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Metastases to the female genital tract are rare, with metastatic disease restricted to the uterus being even less frequent. The primary tumor is most often intragenital rather than extragenital. The diagnosis is usually made after occurrence of gynecological symptoms. We describe the case of a 26-year-old female, in whom a curettage for menorrhagia revealed a uterine malignancy, at first thought to be a carcinosarcoma. Biochemistry only showed iron deficiency anemia. Imaging showed discrepant results with liver lesions, suspect of neoplastic or inflammatory disease. She underwent an abdominal hysterectomy and, peroperatively, a frozen section of a mass in the liver hilus demonstrated a cholangiocarcinoma. The diagnosis of a uterine metastasized cholangiocarcinoma was made. We emphasize the fact that uterine metastases have to be excluded in every woman with abnormal uterine bleeding and a personal history of malignancy. However, our case also indicates that gynecological metastatic disease may be the first presentation of an extragenital primary neoplasm.

Autor: W. Dendas, L. Cappelle, J. Verguts, and G. Orye



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