Surgical Outcome of Patients with Core-Biopsy-Proven Nonpalpable Breast Carcinoma: A Large Cohort Follow-Up StudyReportar como inadecuado




Surgical Outcome of Patients with Core-Biopsy-Proven Nonpalpable Breast Carcinoma: A Large Cohort Follow-Up Study - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Annals of Surgical Oncology

, Volume 16, Issue 8, pp 2252–2258

First Online: 13 May 2009Received: 22 January 2009Revised: 14 April 2009Accepted: 14 April 2009

Abstract

BackgroundBreast-conserving surgery BCS is the preferred treatment for nonpalpable breast carcinoma.
The outcome, however, may be disappointing.
In this study surgical outcome in a large cohort of patients diagnosed with nonpalpable breast carcinoma is evaluated.

MethodsIn 833 patients with 841 nonpalpable breast carcinomas the number of re-excisions and type of surgical procedures was calculated and summed per patient.
Subsequently, the number of conversions to mastectomy and the number of days until complete tumor removal were analyzed.
In a subgroup analysis the patients with an in situ carcinoma were compared with the patients with an invasive carcinoma.

ResultsThe initial surgery consisted of BCS for 589 tumors 70% and of mastectomy for 242 tumors 29%.
For ten tumors 1% the initial surgery was unknown.
After BCS, 158-589 tumors 27% required a re-excision: 116-337 34% for the in situ carcinomas and 63-504 13% for the invasive carcinomas p = 0.0001.
The number of conversions from BCS to mastectomy was 106-589 18%: 66-241 28% in patients diagnosed with an in situ carcinoma versus 40-348 11% in patients with an invasive carcinoma p = 0.0001.
The median number of days until complete tumor removal was 28, being 38 days for the in situ carcinomas and 25 days for the invasive carcinomas p = 0.0001.

ConclusionsThere is room for improvement in the surgical treatment of nonpalpable breast carcinoma, especially the relatively favorable in situ carcinoma, as it requires significantly more excisions, mastectomies, conversions to mastectomy, and days for complete removal.

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Autor: S. van Esser - N. H. G. M. Peters - M. A. A. J. van den Bosch - W. P. Th. M. Mali - P. H. M. Peeters - I. H. M

Fuente: https://link.springer.com/article/10.1245/s10434-009-0513-6



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