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Journal of Gastrointestinal Surgery

, Volume 19, Issue 8, pp 1513–1521

First Online: 05 May 2015Received: 23 February 2015Accepted: 20 April 2015

Abstract

BackgroundThe relationship between visceral obesity and colon cancer outcome has not been well studied. The goal of this study was to determine the impact of visceral obesity on lymph node LN metastasis and overall survival OS in colon cancer.

Materials and MethodsMetastatic LN ratio MLR was defined as the number of involved nodes by tumor divided by the total number of resected LNs. Visceral VFA and subcutaneous fat areas SFA were determined by measuring abdominal fat volume distribution via CT scan, and visceral obesity was defined as a VFA to total fat area ratio V-T > 0.29.

ResultsIn a multivariate analysis among 186 patients, there were inverse associations between V-T and MLR OR = 0.413, 95 % CI = 0.216–0.789, P = 0.007. Furthermore, patients with visceral obesity tended to have significantly better OS than patients with non-visceral obesity.

ConclusionsHigher V-T ratios which indicate referring to visceral obesity was significantly associated with decreased MLR and better OS for CRC.

KeywordsObesity Visceral fat area Lymph node Metastasis Colon cancer  Download fulltext PDF



Autor: Se Woo Park - Hang Lak Lee - Eun Young Doo - Kang Nyeong Lee - Dae Won Jun - Oh Young Lee - Dong Soo Han - Byung Ch

Fuente: https://link.springer.com/article/10.1007/s11605-015-2834-z



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