Effect of Laparoscopic Roux-en-Y Gastric Bypass Surgery on Obstructive Sleep Apnea in a Chinese Population with Obesity and T2DMReportar como inadecuado

Effect of Laparoscopic Roux-en-Y Gastric Bypass Surgery on Obstructive Sleep Apnea in a Chinese Population with Obesity and T2DM - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Obesity Surgery

, Volume 25, Issue 8, pp 1446–1453

First Online: 14 November 2014


BackgroundBariatric surgery has been reported to be an effective treatment for obstructive sleep apnea OSA. However, this evidence was not enough for different populations. Thus, we conducted a follow-up study to evaluate the effect of bariatric surgery on OSA in a Chinese population with obesity and type 2 diabetes mellitus T2DM.

MethodsFrom May 2011 to March 2014, 72 consecutive subjects with obesity and T2DM were recruited for this study. Before and at least 6 months after the laparoscopic Roux-en-Y gastric bypass LYGB surgery, all subjects were asked to undergo a polysomnography test. During the sleep center visit, anthropometric characteristic data, blood samples, and sleep questionnaires were collected.

ResultsIn total, 44 Chinese participants with OSA were included in the study. Compared with baseline data, the postoperative anthropometric characteristics, blood measurements, and sleep recording data, such as weight, apnea hypopnea index AHI, and insulin resistance index, differed significantly p < 0.001. The change in AHI was correlated significantly with preoperative weight r = 0.298, p < 0.05, preoperative AHI r = 0.729, p < 0.001, preoperative waist circumference r = 0.307, p < 0.05, and preoperative insulin resistance IR index r = −0.301, p < 0.05. Postoperative AHI was correlated significantly with age r = 0.039, p = 0.039 and preoperative AHI r = 0.445, p = 0.002, and the following prediction model was generated: log10 postoperative AHI = 0.626 × log10 preoperative AHI +0.010 × age −0.581.

ConclusionsOur findings indicate that LYGB could be an effective therapeutic intervention in the management of OSA for patients with both obesity and T2DM, and the preoperative AHI and age might be important factors that influence the effort of LYGB.

KeywordsObstructive sleep apnea Bariatric surgery Diabetes mellitus Obesity Prediction model Jianyin Zou and Pin Zhang contributed equally to this manuscript.

Electronic supplementary materialThe online version of this article doi:10.1007-s11695-014-1510-9 contains supplementary material, which is available to authorized users.

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Autor: Jianyin Zou - Pin Zhang - Haoyong Yu - Jianzhong Di - Xiaodong Han - Shankai Yin - Hongliang Yi

Fuente: https://link.springer.com/article/10.1007/s11695-014-1510-9

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