Cancer-related multiple brain infarctions caused by Trousseau syndrome in a patient with metastatic colon cancer: a case reportReportar como inadecuado




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Surgical Case Reports

, 2:91

First Online: 05 September 2016Received: 14 March 2016Accepted: 12 August 2016

Abstract

Thromboembolism that occurs in association with a malignant tumor is known as Trousseau syndrome. We herein present a case of Trousseau syndrome during systemic chemotherapy for metastatic colon cancer. A 65-year-old man with multiple liver metastases underwent primary tumor resection and systemic chemotherapy. Multiple brain infarctions were detected by magnetic resonance imaging immediately after first-line chemotherapy, which was deemed ineffective. There was no evidence of cardioembolic stroke or carotid atherosclerosis. Although the patient was initially asymptomatic, he subsequently developed paralysis. Despite anticoagulant treatment, he developed repeated recurrences of the infarction, and the area of the infarction spread as the liver metastases progressed. The patient’s condition showed no response to an alternative treatment regimen for advanced colon carcinoma. He died approximately 11 months after tumor discovery.

KeywordsMetastatic colorectal cancer Brain infarction Trousseau syndrome Hypercoagulability  Download fulltext PDF



Autor: Takahiko Akiyama - Yuji Miyamoto - Yasuo Sakamoto - Ryuma Tokunaga - Keisuke Kosumi - Hironobu Shigaki - Junji Kurashige -

Fuente: https://link.springer.com/article/10.1186/s40792-016-0217-7







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