The early detection of liver metastasesReportar como inadecuado

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Cancer Imaging

, Volume 2, Issue 2, pp 1–3

First Online: 05 May 2015Accepted: 30 January 2002


Early detection of liver metastases improves outcome in patients treated by chemotherapy, and is also associated with better survival in patients treated surgically. Large liver metastases greater than about 1–2 cm in size should be detectable by optimum quality CT or MRI techniques with a high level of accuracy. Microscopic metastases smaller than 1–2 mm in size are rarely detected by anatomic imaging methods, but are also rarely discovered at surgery or pathology. Alterations in perfusion caused by angiogenesis in microscopic lesions can sometimes be detected using radionuclide or doppler perfusion techniques. Currently, attention is focused on the early and correct diagnosis of lesions in the size range 2 mm to 2 cm. In this size range, superparamagnetic iron oxide SPIO enhanced MRI is probably superior 60% sensitivity to dual phase CT 45% sensitivity when compared with surgery and intraoperative ultrasound. Recent developments in CT and MRI promise some further improvement. The value of ultrasonic contrast agents has been shown in efficacy studies, but they are yet to be assessed against state of the art CT and MRI.

KeywordsLiver metastasis diagnosis imaging This paper is available online at In the event of a change in the URL address, please use the DOI provided to locate the paper.

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Autor: P. J. Robinson


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