The spine in Paget’s diseaseReportar como inadecuado

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Skeletal Radiology

, Volume 36, Issue 7, pp 609–626

First Online: 05 April 2007Received: 30 October 2006Revised: 18 December 2006Accepted: 22 December 2006


Paget’s disease PD is a chronic metabolically active bone disease, characterized by a disturbance in bone modelling and remodelling due to an increase in osteoblastic and osteoclastic activity. The vertebra is the second most commonly affected site. This article reviews the various spinal pathomechanisms and osseous dynamics involved in producing the varied imaging appearances and their clinical relevance. Advanced imaging of osseous, articular and bone marrow manifestations of PD in all the vertebral components are presented. Pagetic changes often result in clinical symptoms including back pain, spinal stenosis and neural dysfunction. Various pathological complications due to PD involvement result in these clinical symptoms. Recognition of the imaging manifestations of spinal PD and the potential complications that cause the clinical symptoms enables accurate assessment of patients prior to appropriate management.

KeywordsPaget’s disease Vertebra Spinal stenosis Magnetic resonance imaging Computed tomography  Download fulltext PDF

Autor: C. Dell’Atti - V. N. Cassar-Pullicino - R. K. Lalam - B. J. Tins - P. N. M. Tyrrell


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