Undifferentiated spondyloarthritis following allogeneic stem cell transplantationReportar como inadecuado




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BMC Musculoskeletal Disorders

, 11:132

First Online: 25 June 2010Received: 06 February 2010Accepted: 25 June 2010

Abstract

BackgroundStem cell transplant has been utilized in the treatment of malignancies and rheumatic disease. Rheumatic disease may be transferred from the donor with active disease or may be developed in a recipient de novo as a late complication of SCT.

Case PresentationWe here report the rare case of a 26-year old male patient, who has been diagnosed with undifferentiated spondyloarthropathy after unique circumstance. The patient suffered from intermittent inflammatory back pain and peripheral joint swelling for several years and did not find relief through multiple emergency room visits at different medical facilities. After a thorough history and physical exam, it was noted that our patient had developed signs of axial disease along with dactylitis and overall that he had been insidiously developing an undifferentiated spondyloarthopathy after allogeneic stem cell transplantation.

ConclusionOur observation supports the hypothesis that de novo rheumatic disease can develop after stem cell transplant for a variety of reasons. Thus, larger studies and awareness of this association are needed to delineate the exact underlying mechanisms.

AbbreviationsSCTstem cell transplant.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2474-11-132 contains supplementary material, which is available to authorized users.

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Autor: Vijay R Karia - Raquel Cuchacovich - Luis R Espinoza

Fuente: https://link.springer.com/







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