Image quality and diagnostic accuracy of unenhanced SSFP MR angiography compared with conventional contrast-enhanced MR angiography for the assessment of thoracic aortic diseasesReportar como inadecuado




Image quality and diagnostic accuracy of unenhanced SSFP MR angiography compared with conventional contrast-enhanced MR angiography for the assessment of thoracic aortic diseases - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

European Radiology

, Volume 20, Issue 6, pp 1311–1320

First Online: 16 December 2009Received: 04 June 2009Revised: 26 August 2009Accepted: 30 September 2009

Abstract

ObjectivesThe purpose of this study was to determine the image quality and diagnostic accuracy of three-dimensional 3D unenhanced steady state free precession SSFP magnetic resonance angiography MRA for the evaluation of thoracic aortic diseases.

MethodsFifty consecutive patients with known or suspected thoracic aortic disease underwent free-breathing ECG-gated unenhanced SSFP MRA with non-selective radiofrequency excitation and contrast-enhanced CE MRA of the thorax at 1.5 T.
Two readers independently evaluated the two datasets for image quality in the aortic root, ascending aorta, aortic arch, descending aorta, and origins of supra-aortic arteries, and for abnormal findings.
Signal-to-noise ratio SNR and contrast-to-noise ratio CNR were determined for both datasets.
Sensitivity, specificity, and diagnostic accuracy of unenhanced SSFP MRA for the diagnosis of aortic abnormalities were determined.

ResultsAbnormal aortic findings, including aneurysm n = 47, coarctation n = 14, dissection n = 12, aortic graft n = 6, intramural hematoma n = 11, mural thrombus in the aortic arch n = 1, and penetrating aortic ulcer n = 9, were confidently detected on both datasets.
Sensitivity, specificity, and diagnostic accuracy of SSFP MRA for the detection of aortic disease were 100% with CE-MRA serving as a reference standard.
Image quality of the aortic root was significantly higher on SSFP MRA P < 0.001 with no significant difference for other aortic segments P > 0.05.
SNR and CNR values were higher for all segments on SSFP MRA P < 0.01.

ConclusionOur results suggest that free-breathing navigator-gated 3D SSFP MRA with non-selective radiofrequency excitation is a promising technique that provides high image quality and diagnostic accuracy for the assessment of thoracic aortic disease without the need for intravenous contrast material.

KeywordsSSFP MR angiography Unenhanced MRA Thoracic aorta Contrast Enhanced MRA Steady state free precession  Download fulltext PDF



Autor: Mayil S. Krishnam - Anderanik Tomasian - Sachin Malik - Vibhas Desphande - Gerhard Laub - Stefan G. Ruehm

Fuente: https://link.springer.com/



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