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Pediatric Rheumatology

, 10:3

First Online: 12 January 2012Received: 31 October 2011Accepted: 12 January 2012

Abstract

BackgroundChildren with physical disabilities may have an increased risk for obesity and obesity might be a risk factor for inflammatory arthritis. The aims of this study were: to determine the prevalence of obesity in children and adolescents with juvenile idiopathic arthritis JIA, and to examine the association between obesity and disease activity in this population.

FindingsA cross-sectional analysis of all patients with JIA attending a pediatric rheumatology clinic, between October 2009 and September 2010, was performed. A linear regression model was used to explore the association between obesity and disease activity in patients with JIA. A total of 154 subjects were included in the analysis; median age was 10.6 years, 61% were female, and 88% were white. Obesity was found in 18%, 12% were overweight, and 3% were underweight. There was no association between obesity and JADAS-27 Juvenile Arthritis Disease Activity Score 27, physician-s assessment of disease activity, parent-s assessment of child-s well-being, erythrocyte sedimentation rate, number of active joints, or C-reactive protein p-value range 0.10 to 0.95.

ConclusionsAlthough 18% of patients with JIA were obese, we did not find an association between obesity and disease activity. As obesity confers an additional health risk in children with arthritis, addressing this co-morbidity should be a health priority in patients with JIA. Future studies are necessary to further explore potential associations between obesity, development of JIA, and disease activity.

KeywordsObesity Overweight Arthritis Juvenile Rheumatoid Rheumatology Child Inflammation List of abbreviationsJIAjuvenile idiopathic arthritis

RArheumatoid arthritis

BMIBody mass index

JADAS- 27Juvenile Arthritis Disease Activity Score 27

VASvisual analog scale

ESRerythrocyte sedimentation rate

CRPC-reactive protein value.

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Autor: Christina F Pelajo - Jorge M Lopez-Benitez - Laurie C Miller

Fuente: https://link.springer.com/







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