Differences in MRI findings between subgroups of recent-onset childhood arthritisReport as inadecuate




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Pediatric Radiology

, Volume 41, Issue 4, pp 432–440

First Online: 07 December 2010Received: 06 March 2010Revised: 28 September 2010Accepted: 28 September 2010

Abstract

BackgroundMRI is sensitive for joint inflammation, but its ability to separate subgroups of arthritis in children has been questioned. Infectious arthritis IA, postinfectious arthritis PA, transient arthritis TA and juvenile idiopathic arthritis JIA are subgroups that may need early, different treatment.

ObjectiveTo determine whether MRI findings differ in IA, PA-TA and JIA in recent-onset childhood arthritis.

Materials and methodsFifty-nine children from a prospective study of incidence of arthritis n = 216 were, based on clinical and biochemical criteria, examined by MRI. Joint fluid, synovium, bone marrow, soft tissue and cartilage were scored retrospectively and analysed by Pearson chi-square test and logistic regression analysis.

ResultsFifty-nine children had MRI of one station. IA was suggested by bone marrow oedema OR 7.46, P = 0.011 and absence of T1-weighted and T2-weighted low signal intensity synovial tissue OR 0.06, P = 0.015. Furthermore, soft-tissue oedema and reduced contrast enhancement in the epiphyses were more frequent in children with IA. JIA correlated positively with low signal intensity synovial tissue OR 13.30, P < 0.001 and negatively with soft-tissue oedema OR 0.20, P = 0.018. No significant positive determinants were found for PA-TA, but bone marrow oedema, soft-tissue oedema, irregular thickened synovium and low signal intensity synovial tissue was less frequent than in IA-JIA.

ConclusionIn children with high clinical suspicion of recent onset arthritis, there was a significant difference in the distribution of specific MRI features among the diagnostic groups.

KeywordsSeptic arthritis Juvenile idiopathic arthritis MRI Child Transient arthritis  Download fulltext PDF



Author: Eva Kirkhus - Berit Flatø - Øystein Riise - Tor Reiseter - Hans-Jørgen Smith

Source: https://link.springer.com/







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