Interobserver Variability in Chest CT and Whole Body FDG-PET Screening for Distant Metastases in Head and Neck Cancer PatientsReport as inadecuate




Interobserver Variability in Chest CT and Whole Body FDG-PET Screening for Distant Metastases in Head and Neck Cancer Patients - Download this document for free, or read online. Document in PDF available to download.

Molecular Imaging and Biology

, Volume 13, Issue 2, pp 385–390

First Online: 09 June 2010

Abstract

PurposeThe aim of the study was to assess the interobserver variability in chest computed tomography CT and whole body 2-deoxy-2-Ffluoro-d-glucose positron emission tomography FDG-PET screening for distant metastases in head and neck squamous cell carcinoma HNSCC patients.

ProcedureChest CT and whole body FDG-PET of 69 HNSCC patients with high-risk factors who underwent screening for distant metastases were analyzed. All scans were independently read by two experienced radiologists or nuclear physicians who were blinded to the other examinations and follow-up results.

ResultsA kappa of 0.516 was found for assessment of size on CT. Kappa values for origin and susceptibility of 0.406 and 0.512 for CT and 0.834 and 0.939 for PET were found, respectively. The overall conclusions had a kappa of 0.517–0.634 for CT and 0.820–1.000 for PET.

ConclusionsIn screening for distant metastases in HNSCC patients with high-risk factors, chest CT readings had a reasonable to substantial agreement, while PET readings showed an almost perfect agreement. These findings suggest that for optimal assessment in clinical practice, PET most often can be scored by one observer, but CT should probably more often be scored by different observers in consensus or combined with PET.

Key wordsCT FDG-PET Interobserver agreement Distant metastases Head and neck cancer  Download fulltext PDF



Author: Asaf Senft - Remco de Bree - Richard P. Golding - Emile F. I. Comans - Jan-Hein T. M. Van Waesberghe - J. Dirk Kuik

Source: https://link.springer.com/







Related documents