Value of black blood T2* cardiovascular magnetic resonanceReport as inadecuate

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Journal of Cardiovascular Magnetic Resonance

, 13:21

First Online: 14 March 2011Received: 17 December 2010Accepted: 14 March 2011


PurposeTo assess whether black blood T2* cardiovascular magnetic resonance is superior to conventional white blood imaging of cardiac iron in patients with thalassaemia major TM.

Materials and methodsWe performed both conventional white blood and black blood T2* CMR sequences in 100 TM patients to determine intra and inter-observer variability and presence of artefacts. In 23 patients, 2 separate studies of both techniques were performed to assess interstudy reproducibility.

ResultsCardiac T2* values ranged from 4.5 to 43.8 ms. The mean T2* values were not different between black blood and white blood acquisitions 20.5 vs 21.6 ms, p = 0.26. Compared with the conventional white blood diastolic acquisition, the coefficient of variance of the black blood CMR technique was superior for intra-observer reproducibility 1.47% vs 4.23%, p < 0.001, inter-observer reproducibility 2.54% vs 4.50%, p < 0.001 and inter-study reproducibility 4.07% vs 8.42%, p = 0.001. Assessment of artefacts showed a superior score for black blood vs white blood scans 4.57 vs 4.25; p < 0.001.

ConclusionsBlack blood T2* CMR has superior reproducibility and reduced imaging artefacts for the assessment of cardiac iron, in comparison with the conventional white blood technique, which make it the preferred technique for clinical practice.

Electronic supplementary materialThe online version of this article doi:10.1186-1532-429X-13-21 contains supplementary material, which is available to authorized users.

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Author: Gillian C Smith - John Paul Carpenter - Taigang He - Mohammed H Alam - David N Firmin - Dudley J Pennell


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