Long-term MRA follow-up after coiling of intracranial aneurysms: impact on mood and anxietyReport as inadecuate

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, Volume 53, Issue 5, pp 343–348

First Online: 23 June 2010Received: 02 March 2010Accepted: 26 May 2010


IntroductionMagnetic resonance angiography MRA screening for recurrence of a coiled intracranial aneurysm and formation of new aneurysms long-term after coiling may induce anxiety and depression. In coiled patients, we evaluated effects on mood and level of anxiety from long-term follow-up MRA in comparison to general population norms.

MethodsOf 162 patients participating in a long-term >4.5 years MRA follow-up after coiling, 120 completed the EQ-5D questionnaire, a visual analog health scale and a self-developed screening related questionnaire at the time of MRA. Three months later, the same questionnaires were completed by 100 of these 120 patients. Results were compared to general population norms adjusted for gender and age.

ResultsAny problem with anxiety or depression was reported in 56 of 120 patients 47%; 95%CI38↔56% at baseline and 42 of 100 patients 42%; 95%CI32↔52% at 3 months, equally for screen-positives and -negatives. Compared to the reference population, participants scored 38% 95%CI9↔67% and 27% 95%CI4↔50% more often any problem with anxiety or depression. Three months after screening, 21% 20 of 92 of screen-negatives and 13% one of eight of screen-positives reported to be less afraid of subarachnoid hemorrhage SAH compared to before screening. One of eight screen-positives reported increased fear of SAH.

ConclusionsPatients with coiled intracranial aneurysms participating in long-term MRA screening reported significantly more often to be anxious or depressed than a reference group. Screening did not significantly increase anxiety or depression temporarily. However, subjectively, patients did report an increase in anxiety caused by screening, which decreased after 3 months.

KeywordsCoiling Magnetic resonance angiography MRA Screening EQ-5D questionnaire Anxiety AbbreviationsMRAmagnetic resonance angiography

SAHsubarachnoid hemorrhage

MRImagnetic resonance imaging

TOF MRAtime-of-flight MRA

VASvisual analog scale

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Author: Sandra P. Ferns - Pythia T. Nieuwkerk - Willem Jan J. van Rooij - Gabriël J. E. Rinkel - Charles B. L. M. Majoie

Source: https://link.springer.com/

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