Predictive factors for new onset or progression of knee osteoarthritis one year after trauma: MRI follow-up in general practiceReport as inadecuate




Predictive factors for new onset or progression of knee osteoarthritis one year after trauma: MRI follow-up in general practice - Download this document for free, or read online. Document in PDF available to download.

European Radiology

, Volume 21, Issue 7, pp 1509–1516

First Online: 06 March 2011Received: 14 October 2010Revised: 19 December 2010Accepted: 16 January 2011

Abstract

ObjectiveTo prospectively evaluate prognostic factors for new onset or progression of degenerative change on follow-up MRI one year after knee trauma and the association with clinical outcome.

MethodsWithin a prospective observational cohort study in general practice, we studied a subgroup of 117 patients with acute knee trauma mean age 41 years, 43% women. Degenerative change was scored on MRI at baseline and after one year follow-up. Multivariate logistic regression analysis was performed to evaluate prognostic factors for new onset or progressive degenerative change on follow-up MRI. Association between new or progressive degeneration and clinical outcome after one year was assessed.

ResultsOn follow-up MRI 15% of patients with pre-existing knee osteoarthritis showed progression and 26% of patients demonstrated new degenerative change. The only statistically significant prognostic variable in the multivariate analysis was bone marrow oedema on initial MRI OR 5.29 95% CI 1.64–17.1, p = 0.005. A significant association between new or progressive degenerative change and clinical outcome was found p = 0.003.

ConclusionBone marrow oedema on MRI for acute knee injury is strongly predictive of new onset or progression of degenerative change of the femorotibial joint on follow-up MRI one year after trauma, which is reflected in clinical outcome.

KeywordsKnee injury Osteoarthritis MRI Follow-up Clinical outcome  Download fulltext PDF



Author: Ingrid M. Koster - Edwin H. G. Oei - Jan-Hein J. Hensen - Simone S. Boks - Bart W. Koes - Dammis Vroegindeweij - M. G

Source: https://link.springer.com/







Related documents