CT of the hips in the investigation of protrusio acetabuli in Marfan syndrome. A case control studyReport as inadecuate

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European Radiology

, Volume 21, Issue 7, pp 1485–1491

First Online: 14 February 2011Received: 28 September 2010Revised: 10 December 2010Accepted: 06 January 2011


ObjectivesTo establish the prevalence of protrusio acetabuli PA in adults fulfilling the Ghent criteria for Marfan syndrome MFS, and in a normal adult population.

Methods105 adults with probable MFS and 107 controls were included. CT of the hips was obtained. A qualitative assessment of PA was performed. A new method for estimating the degree of PA was introduced with measurement of the parameter CWD circle-wall distance. Results were compared to an alternative method based on MRI 1.

Results87 of the study group fulfilled the Ghent criteria of MFS Ghent positives, and 18 did not Ghent negatives. PA was diagnosed qualitatively in 74.7% of Ghent positive persons, in 27.8% of Ghent negative persons, and in 3.7% of the controls. CWD was significantly different between the three groups p < 0.001. A slight but significant gender difference was found in Ghent positive persons only. The alternative method did not differentiate between the groups with respect to PA, but showed a significant difference between genders.

ConclusionsPA was found significantly more often in MFS persons than in controls. Our method was found to be robust and highly reproducible, giving a direct measurement of pelvic protrusion irrespective of pelvic shape.

KeywordsMarfan Syndrome Computed tomography CT Hip joint Pelvic bones Connective tissue diseases  Download fulltext PDF

Author: Rigmor Lundby - Eva Kirkhus - Svend Rand-Hendriksen - John Hald - Are Hugo Pripp - Hans-Jørgen Smith

Source: https://link.springer.com/

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