Does moderate or severe nonspecific knee injury affect radiographic osteoarthritis incidence and progressionReportar como inadecuado




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BMC Musculoskeletal Disorders

, 14:309

Epidemiology of musculoskeletal disorders

Abstract

BackgroundKnee injuries can lead to radiographic osteoarthritis ROA. Injuries may be -specific- SI including ligament or meniscal tears or patellar trauma, or -nonspecific- NSI. Our objective is to understand the effect of knee NSI on ROA incidence and progression.

Methods163 people sample-weighted for population representativeness aged 40+ with history of knee pain had radiographs assessed on Kellgren Lawrence KL grade 0-1 collapsed at baseline and follow-up median 3.2 years apart. Progression was an increase in KL score. SIs and NSIs were labeled -severe- walking aid for ≥1 week or -moderate-. One model treated SI and NSI as dichotomous yes-no, and another as trichotomous none-moderate-severe. Models were adjusted for age, sex, BMI, KL grade and follow-up time.

ResultsSI-NSI history was none, moderate 7.8-24.4% or severe 11.0-10.8%. Duration at baseline since SI-NSI ranged from <1 year to several decades SI-NSI mean 4.6-6.5 years. SI was significantly associated with ROA incidence and progression odds ratio OR = 2.90; 95% CI = 1.04, 8.09, but NSI showed no significant effect OR = 1.36; 95% CI = 0.61, 3.02. In the trichotomous model, severe SI was significant OR = 4.35, 95% CI = 1.26, 15.02, while moderate SI was not OR = 1.51, 95% CI = 0.33, 6.84. NSI showed no effect: moderate OR = 1.51, 95% CI = 0.61, 3.74; severe OR = 0.90, 95% CI = 0.24, 3.40. This study had 80% power to detect an NSI OR of 2.9.

ConclusionWe find no evidence that history of NSI affects knee ROA incidence and progression in a population with knee pain, adjusting for SI, age, sex, BMI, KL grade and follow-up time.

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Autor: Eric C Sayre - Joel Singer - Anona Thorne - Hubert Wong - Jacek A Kopec - John M Esdaile - Ali Guermazi - Savvas Nicola

Fuente: https://link.springer.com/







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