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Arthritis Research and Therapy

, 15:120

First Online: 29 October 2013


Osteoarthritis is becoming more problematic as the population ages. Recent reports suggest that the benefit of anti-inflammatory drugs is unimpressive and the incidence of side effects is worrying. Low-level laser light therapy LLLT is an alternative approach with no known side effects and with reports of substantial therapeutic efficacy in osteoarthritis. In this issue of Arthritis Research and Therapy, Alves and colleagues used a rat model of osteoarthritis produced by intra-articular injection of the cartilage-degrading enzyme papain to test 810-nm LLLT. A single application of LLLT produced significant reductions in inflammatory cell infiltration and inflammatory cytokines 24 hours later. A lower laser power was more effective than a higher laser power. However, more work is necessary before the title question can be answered in the affirmative.


LLLTLow-level laser light therapy

NSAIDNon-steroidal anti-inflammatory drug

TNF-αTumor necrosis factor-alpha.

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Autor: Michael R Hamblin


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