Cardiac-respiratory self-gated cine ultra-short echo time UTE cardiovascular magnetic resonance for assessment of functional cardiac parameters at high magnetic fieldsReportar como inadecuado




Cardiac-respiratory self-gated cine ultra-short echo time UTE cardiovascular magnetic resonance for assessment of functional cardiac parameters at high magnetic fields - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Journal of Cardiovascular Magnetic Resonance

, 15:59

First Online: 04 July 2013Received: 14 May 2013Accepted: 19 June 2013

Abstract

BackgroundTo overcome flow and electrocardiogram-trigger artifacts in cardiovascular magnetic resonance CMR, we have implemented a cardiac and respiratory self-gated cine ultra-short echo time UTE sequence. We have assessed its performance in healthy mice by comparing the results with those obtained with a self-gated cine fast low angle shot FLASH sequence and with echocardiography.

Methods2D self-gated cine UTE TE-TR = 314 μs-6.2 ms, resolution: 129 × 129 μm, scan time per slice: 5 min 5 sec and self-gated cine FLASH TE-TR = 3 ms-6.2 ms, resolution: 129 × 129 μm, scan time per slice: 4 min 49 sec images were acquired at 9.4 T. Volume of the left and right ventricular LV, RV myocardium as well as the end-diastolic and -systolic volume was segmented manually in MR images and myocardial mass, stroke volume SV, ejection fraction EF and cardiac output CO were determined. Statistical differences were analyzed by using Student t test and Bland-Altman analyses.

ResultsSelf-gated cine UTE provided high quality images with high contrast-to-noise ratio CNR also for the RV myocardium CNRblood-myocardium = 25.5 ± 7.8. Compared to cine FLASH, susceptibility, motion, and flow artifacts were considerably reduced due to the short TE of 314 μs. The aortic valve was clearly discernible over the entire cardiac cycle. Myocardial mass, SV, EF and CO determined by self-gated UTE were identical to the values measured with self-gated FLASH and showed good agreement to the results obtained by echocardiography.

ConclusionsSelf-gated UTE allows for robust measurement of cardiac parameters of diagnostic interest. Image quality is superior to self-gated FLASH, rendering the method a powerful alternative for the assessment of cardiac function at high magnetic fields.

KeywordsHigh magnetic field Flow artifacts Cardiovascular magnetic resonance Retrospective gating Self-gated cine UTE Electronic supplementary materialThe online version of this article doi:10.1186-1532-429X-15-59 contains supplementary material, which is available to authorized users.

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Autor: Verena Hoerr - Nina Nagelmann - Arno Nauerth - Michael T Kuhlmann - Jörg Stypmann - Cornelius Faber

Fuente: https://link.springer.com/



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