Clinical validation of free breathing respiratory triggered retrospectively cardiac gated cine balanced steady-state free precession cardiovascular magnetic resonance in sedated childrenReportar como inadecuado




Clinical validation of free breathing respiratory triggered retrospectively cardiac gated cine balanced steady-state free precession cardiovascular magnetic resonance in sedated children - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Journal of Cardiovascular Magnetic Resonance

, 17:1

First Online: 14 January 2015Received: 14 April 2014Accepted: 21 November 2014

Abstract

BackgroundCine balanced steady-state free precession SSFP, the preferred sequence for ventricular function, demands uninterrupted radio frequency RF excitation to maintain the steady-state during suspended respiration.
This is difficult to accomplish in sedated children.
In this work, we validate a respiratory triggered RT SSFP sequence that drives the magnetization to steady-state before commencing retrospectively cardiac gated cine acquisition in a sedated pediatric population.

MethodsThis prospective study was performed on 20 sedated children with congenital heart disease 8.6 ± 4 yrs.
Identical imaging parameters were used for multiple number of signal averages MN and RT cine SSFP sequences covering both the ventricles in short-axis SA orientation.
Image quality assessment and quantitative volumetric analysis was performed on the datasets by two blinded observers.
One-sided Wilcoxon signed rank test and Box plot analysis were performed to compare the clinical scores.
Bland-Altman BA analysis was performed on LV and RV volumes.

ResultsScan duration for SA stack using RT-SSFP 3.9 ± 0.8 min was slightly shorter than MN-SSFP 4.6 ± 0.9 min acquisitions.
The endocardial edge definition was significantly better for RT than MN, blood to myocardial contrast was better for RT than MN without reaching statistical significance, and inter slice alignment was comparable.
BA analysis indicates that the variability of volumetric indices between RT and MN is comparable to inter and intra-observer variability reported in the literature.

ConclusionsThe free breathing RT-SSFP sequence allows diagnostic images in sedated children with significantly better edge definition when compared to MN-SSFP, without any penalty for total scan time.

KeywordsRespiratory triggered cine SSFP Congenital heart disease Cardiovacualr magnetic resonance Sequence Pediatrics AbbreviationsSSFPSteady state free precession

RTRespiratory triggered

NSANumber of signal averages

MNMultiple NSA

EdefEdge definition

BMCBlood myocardial contrast

ISAInter-slice alignment

VCGVector electrocardiographic gating

RFRadio frequency

LVLeft ventricle

RVRight ventricle

SAShort axis

CMRCardiovascular magnetic resonance

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Autor: Rajesh Krishnamurthy - Amol Pednekar - Lamya A Atweh - Esben Vogelius - Zili David Chu - Wei Zhang - Shiraz Maskatia - Pr

Fuente: https://link.springer.com/article/10.1186/s12968-014-0101-1



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