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BMC Musculoskeletal Disorders

, 17:163

Epidemiology of musculoskeletal disorders


BackgroundThe aim was to assess time trend of mortality with musculoskeletal disorders MSD as underlying cause of death in Sweden from 1997 to 2013.

MethodsWe obtained data on MSD as underlying cause of death across age and sex groups from the National Board of Health and Welfare-s Cause of Death Register. Age-standardized mortality rates per million population for all MSD, its six major subgroups, and all other ICD-10 International Classification of Disease chapters were calculated. We computed the average annual percent change AAPC in the mortality rates across age-sex groups using joinpoint regression analysis by fitting a regression line to the natural logarithm of the age-standardized mortality rates and calendar year as a predictor.

ResultsThere were a total of 7 976 deaths 0.5 % of all causes deaths with MSD as the underlying cause of death 32.5 % of these deaths caused by rheumatoid arthritis RA. The overall age-standardized mortality rates 95 % CI were 16.0 15.4 to 16.7 and 24.9 24.1 to 25.7 per million among men and women, respectively women-men rate ratio 1.55; 95%CI 1.47 to 1.63. On average, mortality rate declined by 2.3 % per year and only circulatory system mortality had a more favourable decline than mortality with MSD as underlying cause. Among MSD the highest decline was observed in RA 3.7 % per year during study period. Across age groups, while there were generally stable or declining trends, spondylopathies and osteoporosis mortality among people ≥ 75 years increased by 2 and 1.5 % per year, respectively.

ConclusionIn overall, mortality with MSD as underlying cause has declined in Sweden over last two decades, with the highest decline for RA. However, there are variations across MSD subgroups which warrants further investigations.

KeywordsMortality Musculoskeletal disorders Temporal trend Sweden AbbreviationsAAPCaverage annual percent change

APCannual percent change

CIconfidence interval

DALYsdisability-adjusted life years

ICD-10International Classification of Disease, the10th revision

MSDmusculoskeletal disorders


RArheumatoid arthritis

WHOWorld Health Organization

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Autor: Aliasghar A. Kiadaliri - Martin Englund


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