Novel Software-Assisted Hemodynamic Evaluation of Pelvic Flow During Chemoperfusion of Pelvic Arteries for Bladder Cancer: Double- Versus Single-Balloon TechniqueReportar como inadecuado




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CardioVascular and Interventional Radiology

, Volume 39, Issue 6, pp 824–830

First Online: 27 January 2016Received: 14 August 2015Accepted: 07 January 2016

Abstract

PurposeApproximately 83 % of patients with bladder cancer have achieved a complete response after undergoing a novel bladder preservation therapy involving balloon-occluded intra-arterial infusion chemotherapy BOAI using a four-lumen double-balloon catheter, known as the Osaka Medical College regimen. This study aimed to show the quantitative difference in hemodynamics of the bladder arteries using syngo iFlow Siemens Healthcare, Erlangen, Germany, which provides an automatic tool for quantitative blood flow analysis between double BOAI D-BOAI and conventional single BOAI S-BOAI.

Materials and MethodsFifty patients were included. The catheters were introduced into both posterior trunks of the internal iliac arteries via contralateral femoral artery access. A side hole between the distal and proximal balloons was placed at the origin of each bladder artery to allow clear visualization of angiographic flow of the injected agent into the urinary bladder. Digital subtraction angiography was used during analysis with the syngo iFlow to evaluate the hemodynamics of the contrast medium in the pelvic arteries during BOAI. The comparative change in the amount of contrast medium in the bladder arteries between D-BOAI and S-BOAI was assessed using syngo iFlow.

ResultsOne-hundred pelvic sides were analyzed. The amount of contrast medium in the bladder arteries using D-BOAI was more than twice that using S-BOAI right, 3.03-fold; left, 2.81-fold.

ConclusionThe amount of contrast medium in the bladder arteries using D-BOAI was higher than that using conventional S-BOAI. This may increase the anticancer drug concentration in the affected bladder, leading to a good clinical response.

KeywordsInvasive bladder cancer Double balloon-occluded arterial infusion Syngo iFlow  Download fulltext PDF



Autor: Kiyohito Yamamoto - Kazuhiro Yamamoto - Go Nakai - Haruhito Azuma - Yoshifumi Narumi

Fuente: https://link.springer.com/



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