Evaluation of right ventricular function in fetal hypoplastic left heart syndrome using spatio-temporal image correlation STICReportar como inadecuado




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Cardiovascular Ultrasound

, 14:12

First Online: 11 April 2016Received: 29 January 2016Accepted: 02 April 2016

Abstract

BackgroundPostnatal outcome of fetuses with hypoplastic left heart syndrome HLHS is mainly determined by right ventricular function. In the present study we used spatio-temporal image correlation STIC to assess right ventricular function of fetuses with HLHS.

MethodsThree-dimensional ultrasound with STIC technique was used to acquire heart images from fetuses that had HLHS and the normal controls, between 24 and 37 weeks of gestation. Right ventricular end-diastolic volume RVEDV and right ventricular end-systolic volume RVESV were determined using the virtual organ computer-aided analysis software, and the parameters of right ventricular function were calculated.

ResultsBoth RVEDV and RVESV were found to be significantly higher in fetuses with HLHS as compared to that in normal controls P < 0.001. There were no significant differences in the parameters between fetuses with and without a visible left ventricular cavity P > 0.05. Compared to fetuses with HLHS plus mild tricuspid regurgitation TR, fetuses with HLHS plus severe TR exhibited lower right ventricular stroke volume RVSV, right ventricular cardiac output RVCO and standardized RVCO P < 0.05. The right ventricular ejection fraction RVEF was significantly lower in HLHS fetuses that had severe TR P < 0.001.

ConclusionAs the right ventricle is solely responsible for maintenance of circulation, the right ventricular systolic function undergoes compensatory enhancement in fetuses with HLHS and mild TR, compared to that in normal controls. Size of the left ventricle does not significantly affect the right ventricular function in HLHS. However, right ventricular systolic function may be impaired prenatally in HLHS fetuses that have severe TR.

KeywordsFetal hypoplastic left heart syndrome Right ventricular function Spatio-temporal image correlation  Download fulltext PDF



Autor: Jing Zhang - Qichang Zhou - Yili Zhao - Qinghai Peng - Zheli Gong - Xiangdang Long

Fuente: https://link.springer.com/article/10.1186/s12947-016-0056-5



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