Clinical and economic burden of idiopathic pulmonary fibrosis: a retrospective cohort studyReportar como inadecuado

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BMC Pulmonary Medicine

, 16:2

Infectious, Rare and Idiopathic Pulmonary Diseases


BackgroundIdiopathic pulmonary fibrosis IPF is a devastating condition with a variable course. Not uncommonly, IPF patients are hospitalized for respiratory-related causes, including disease worsening. This study aimed to characterize the prevalence, and economic and health care burden of IPF.

MethodsRetrospective insurance claims data collected yearly between January 1, 2009 and December 31, 2011, were used to determine prevalence and calculate all-cause and respiratory-related resource utilization and costs. Patients had at least one inpatient claim or two outpatient claims for IPF ICD-9-CM code 516.3. Results for health care burden are reported for the 2011 cohort similar findings in 2009–2010. Costs are reported in 2011 US dollars $.

ResultsPatients with IPF had a mean age of 69.8–71.3 years. Overall prevalence for IPF was 28.8, 28.1 and 19.8 per 100,000 insured persons in 2009, 2010 and 2011. In each year, prevalence increased with age. In 2011, 37.7 % of patients were hospitalized at least once for any cause; 19.5 % for respiratory-related reasons. Also in 2011, the mean number of all-cause outpatient visits and respiratory-related office visits was 18.5 and 5.7 per patient, respectively. All-cause health care costs in 2011 were $59,379 per patient; 36.6 % of costs $21,732 were respiratory related.

ConclusionsThe prevalence of IPF in this claims database increased with age, with a notable increase in those over 65 years. IPF is associated with a large economic and health care burden. Additional research is needed to determine how such burden might be reduced.

KeywordsIdiopathic pulmonary fibrosis Health care resource utilization Health care costs AbbreviationCCICharlson comorbidity index

EDEmergency department

HIPAAHealth insurance portability and accountability act

ICD-9-CMInternational classification of diseases, ninth revision, clinical modification

ILDInterstitial lung disease

IPFIdiopathic pulmonary fibrosis

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Autor: Karina Raimundo - Eunice Chang - Michael S. Broder - Kimberly Alexander - James Zazzali - Jeffrey J. Swigris


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