Implementation of GOLD consensus report in real life: results from the Velletri-Lariano VELA cohortReportar como inadecuado

Implementation of GOLD consensus report in real life: results from the Velletri-Lariano VELA cohort - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Multidisciplinary Respiratory Medicine

, 12:18

First Online: 17 July 2017Received: 20 December 2016Accepted: 22 April 2017


BackgroundCOPD is one of the leading causes of morbidity and mortality. Pharmacotherapy improves quality of life and reduces exacerbations although low adherence with prescribed treatments may represent a barrier to optimal disease management.

The first objective of this paper is to report the distribution of COPD patients according to GOLD categories, in a sample of patients from a cohort study in an area of the Latium region in Italy. The second objective is to evaluate the agreement between the distributions of severity obtained from the HCPs and the experts included in the study board Board.

MethodsCOPD patients were given a card to collect demographic and clinical data at baseline. Information in those cards was independently evaluated by HCPs and Board to include each patient into one of the four GOLD categories.

ResultsIn a sample of 187 stable COPD patients, 59% male, mean age 70 year, the distribution of GOLD categories according to the Board was: 6% A, 34% B, 2% C, and 58% D. A discrepancy in GOLD classification was observed between the study board and field-based HCPs, regarding more than 50% of the patients, with a clear trend to underestimate the frequency of patients in D level 21% and to overestimate the frequency in C level 21%.

ConclusionsThese results describe for the first time the distribution of COPD patients in an Italian cohort according to the GOLD categories, with the highest frequencies in levels B and D. The misclassification from HCPs may impact the therapeutic approach and the clinical outcomes.

KeywordsCOPD Exacerbations Co-morbidities CAT GOLD guidelines AbbreviationsCATCOPD assessment test

FEV1Forced expiratory volume in the first second

GOLDGlobal Initiative for Chronic Obstructive Lung Disease

HCPHealth care provider

mMRCModified Medical Research Council

SaO2Oxygen saturation


Download fulltext PDF

Autor: G. De Filippi - M. Lallini - G. De Riggi - G. Marchetti - C. M. Dimartino - A. M. Russetti - E. Ferrari - R. Pistelli -


Documentos relacionados