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BMC Genetics

, 8:4

First Online: 23 February 2007Received: 20 September 2006Accepted: 23 February 2007

Abstract

BackgroundDiseases of cartilage, such as arthritis and degenerative disc disease, affect the majority of the general population, particularly with ageing. Discovery and understanding of the genes and pathways involved in cartilage biology will greatly assist research on the development, degeneration and disorders of cartilage.

DescriptionWe have established the Integrated Cartilage Gene Database iCartiGD of genes that are known, based on results from high throughput experiments, to be expressed in cartilage. Information about these genes is extracted automatically from public databases and presented as a single page report via a web-browser. A variety of flexible search options are provided and the chromosomal distribution of cartilage associated genes can be presented.

ConclusioniCartiGD provides a comprehensive source of information on genes known to be expressed in cartilage. It will remain current due to its automatic update capability and provide researchers with an easily accessible resource for studies involving cartilage. Genetic studies of the development and disorders of cartilage will benefit from this database.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2156-8-4 contains supplementary material, which is available to authorized users.

Ming-Yiu Yeung, David K Smith contributed equally to this work.

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Autor: Ming-Yiu Yeung - David K Smith - Matthew SY Chan - Cheuk M Li - Brian C Wong - Kenneth MC Cheung - Keith DK Luk - Kat

Fuente: https://link.springer.com/article/10.1186/1471-2156-8-4







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