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International Journal of EndocrinologyVolume 2011 2011, Article ID 898302, 4 pages

Case Report

Endocrine, Bariatric and Metabolic Unit, General Surgery Department, University Hospital Vall d-Hebron, 08035 Barcelona, Spain

Endocrinology Department, University Hospital Vall d-Hebron, 08035 Barcelona, Spain

General Surgery Department, University Hospital Vall d-Hebron, Passeig de la Vall d-Hebron 119-129, 08035 Barcelona, Spain

Pathology Department, University Hospital Vall d-Hebron, 08035 Barcelona, Spain

Received 16 October 2010; Revised 9 December 2010; Accepted 13 January 2011

Academic Editor: Leon Bach

Copyright © 2011 Ramon Vilallonga et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Thyroid gland involvement as the unique presentation of Langerhans cell histiocytosis is a rare phenomenon that can result in misdiagnosis. We report a case of Langerhans cell histiocytosis LCH presenting as a thyroid mass. It is a 52-year-old woman who presented an enlarged, diffusely firm, nontender, nonmobile, and not particularly nodular thyroid gland with mild compressive symptoms. Ultrasound and fine-needle aspiration showed a unique right node with benign signs. Patient was referred to our Ambulatory Surgery Department, where a hemithyroidectomy was performed. Histologic evaluation of the right thyroid gland revealed an involvement by LCH, confirmed by immunohistochemical analysis showing Langerhans cells that were positive for CD1a. LCH was a completelyincidental occult finding apparent only after surgical resection and examination of the gland. Patient was evaluated, and no evidence of systemic affectation was found. LCH can rarely involve the thyroid gland in adults. Few cases have been reported in the literature. Most patients had evidence of LCH involving other anatomic sites.





Autor: Ramon Vilallonga, Andrea Ciudin, José Manuel Fort, Juan Antonio Baena, Oscar Gonzalez, Manuel Armengol, Jordi Mesa, and Ma

Fuente: https://www.hindawi.com/



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