Major genomic mitochondrial lineages delineate early human expansionsReportar como inadecuado




Major genomic mitochondrial lineages delineate early human expansions - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Genetics

, 2:13

First Online: 13 August 2001Received: 09 July 2001Accepted: 13 August 2001

Abstract

BackgroundThe phylogeographic distribution of human mitochondrial DNA variations allows a genetic approach to the study of modern Homo sapiens dispersals throughout the world from a female perspective. As a new contribution to this study we have phylogenetically analysed complete mitochondrial DNAmtDNA sequences from 42 human lineages, representing major clades with known geographic assignation.

ResultsWe show the relative relationships among the 42 lineages and present more accurate temporal calibrations than have been previously possible to give new perspectives as how modern humans spread in the Old World.

ConclusionsThe first detectable expansion occurred around 59,000–69,000 years ago from Africa, independently colonizing western Asia and India and, following this southern route, swiftly reaching east Asia. Within Africa, this expansion did not replace but mixed with older lineages detectable today only in Africa. Around 39,000–52,000 years ago, the western Asian branch spread radially, bringing Caucasians to North Africa and Europe, also reaching India, and expanding to north and east Asia. More recent migrations have entangled but not completely erased these primitive footprints of modern human expansions.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2156-2-13 contains supplementary material, which is available to authorized users.

Download fulltext PDF



Autor: Nicole Maca-Meyer - Ana M González - José M Larruga - Carlos Flores - Vicente M Cabrera

Fuente: https://link.springer.com/article/10.1186/1471-2156-2-13







Documentos relacionados