Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehydeReportar como inadecuado

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E-Journal of Chemistry - Volume 8 2011, Issue 1, Pages 305-311

Department of Pharmacy Shri Govindram Seksaria Institute of Technology and Science, 23-Park Road, Indore-452003, India

Received 23 April 2010; Accepted 17 June 2010

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by taking DMF as solvent and evaluated for their antimicrobial activity. All the synthesized compounds were characterized by IR,

HNMR and mass spectral analysis. All compounds were tested against five gram positive and five gram negative bacterial strains and one fungal strain. All compounds exhibited better activity against gram positive strains than against gram negative strains and the compounds were found more active against S.aureus and B.subtilis.

Autor: Priyanka Kamaria, N. Kawathekar, and Prerna Chaturvedi

Fuente: https://www.hindawi.com/


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