Effect of obesity on constant workrate exercise in hyperinflated men with COPDReportar como inadecuado

Effect of obesity on constant workrate exercise in hyperinflated men with COPD - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Pulmonary Medicine

, 10:33

First Online: 30 May 2010Received: 05 February 2010Accepted: 30 May 2010


BackgroundChronic obstructive pulmonary disease COPD and a high body mass index BMI can both affect pulmonary volumes as well as exercise tolerance, but their combined effect on these outcomes is not well known. The aim of this study was to investigate the effects of increased BMI during constant workrate cycle ergometry in patients with COPD.

MethodsMen with COPD and hyperinflation were divided according to World Health Organization BMI classification: 84 normal BMI NBMI, 130 overweight OW and 64 obese OB. Patients underwent spirometric and lung volumes assessment and an incremental cycling exercise test. This was followed by a constant workrate exercise test CET at 75% of peak capacity. Inspiratory capacity and Borg dyspnea scores were measured at baseline, during and at the end of CET.

Results and discussionFEV1 % predicted was not different across BMI classes. Total lung capacity and functional residual capacity were significantly lower in OB and OW compared to NBMI patients. Peak VO2 in L·min was significantly higher in OB and OW patients than in NBMI patients. CET time was not different across BMI classes p = 0.11. Changes in lung volumes and dyspnea during CET were not different between BMI categories.

ConclusionsOB and OW patients with COPD had a higher peak VO2 than their lean counterparts. Endurance time, dyspnea and changes in lung volumes during CET were similar between BMI categories.

List of abbreviationsBMIbody mass index

CETconstant workrate cycle exercise test

COPDchronic obstructive pulmonary disease

EELVend-expiratory lung volume

EILVend-inspiratory lung volume

FEV1forced expiratory volume in 1 second

FRCfunctional residual capacity

FVCForced vital capacity

ICinspiratory capacity

IRVinspiratory reserve volume

MVVmaximal voluntary ventilation

NBMInormal BMI



RRrespiratory rate

RVresidual volume

SDstandard deviation

SpO2oxygen pulse saturation

TLCtotal lung capacity


VO2oxygen consumption

VTtidal volume.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2466-10-33 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Autor: Louis Laviolette - Francesco Sava - Denis E O-Donnell - Katherine A Webb - Alan L Hamilton - Steven Kesten - François M

Fuente: https://link.springer.com/

Documentos relacionados