Stress-related cardiomyopathiesReportar como inadecuado




Stress-related cardiomyopathies - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Annals of Intensive Care

, 1:39

First Online: 20 September 2011Received: 04 July 2011Accepted: 20 September 2011

Abstract

Stress-related cardiomyopathies can be observed in the four following situations: Takotsubo cardiomyopathy or apical ballooning syndrome; acute left ventricular dysfunction associated with subarachnoid hemorrhage; acute left ventricular dysfunction associated with pheochromocytoma and exogenous catecholamine administration; acute left ventricular dysfunction in the critically ill. Cardiac toxicity was mediated more by catecholamines released directly into the heart via neural connection than by those reaching the heart via the bloodstream. The mechanisms underlying the association between this generalized autonomic storm secondary to a life-threatening stress and myocardial toxicity are widely discussed. Takotsubo cardiomyopathy has been reported all over the world and has been acknowledged by the American Heart Association as a form of reversible cardiomyopathy. Four -Mayo Clinic- diagnostic criteria are required for the diagnosis of Takotsubo cardiomyopathy: 1 transient left ventricular wall motion abnormalities involving the apical and-or midventricular myocardial segments with wall motion abnormalities extending beyond a single epicardial coronary artery distribution; 2 absence of obstructive epicardial coronary artery disease that could be responsible for the observed wall motion abnormality; 3 ECG abnormalities, such as transient ST-segment elevation and-or diffuse T wave inversion associated with a slight troponin elevation; and 4 the lack of proven pheochromocytoma and myocarditis. ECG changes and LV dysfunction occur frequently following subarachnoid hemorrhage and ischemic stroke. This entity, referred as neurocardiogenic stunning, was called neurogenic stress-related cardiomyopathy. Stress-related cardiomyopathy has been reported in patients with pheochromocytoma and in patients receiving intravenous exogenous catecholamine administration. The role of a huge increase in endogenous and-or exogenous catecholamine level in critically ill patients severe sepsis, post cardiac resuscitation, post tachycardia to explain the onset of myocardial dysfunction was discussed. Further research is needed to understand this complex interaction between heart and brain and to identify risk factors and therapeutic and preventive strategies.

Electronic supplementary materialThe online version of this article doi:10.1186-2110-5820-1-39 contains supplementary material, which is available to authorized users.

Download fulltext PDF



Autor: Christian Richard

Fuente: https://link.springer.com/







Documentos relacionados