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Canadian Respiratory Journal - Volume 2017 2017, Article ID 6913564, 5 pages - https:-doi.org-10.1155-2017-6913564

Research Article

Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Disease NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Disease NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Department of Biotechnology, School of Advanced Technology in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Correspondence should be addressed to Payam Mehrian

Received 13 October 2016; Accepted 28 November 2016; Published 3 January 2017

Academic Editor: Sahal Al-Hajoj

Copyright © 2017 Ayeh Baghizadeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Nontuberculous mycobacterial NTM pulmonary infections can be quite similar to tuberculosis, both clinically and radiologically. However, the treatment protocol is not similar. Mycobacterium simiae is a rare cause of NTM pulmonary infection. Herein, we aimed to evaluate and compare the computed tomography CT scan findings of M. simiae infection in lungs. For this reason, thirty-four patients with M. simiae lung infection were retrospectively evaluated. Diagnosis was confirmed by American Thoracic Society ATS guidelines and CT scans were reviewed in both lung and mediastinal windows. The average age of patients was years and 52.9% were male. The majority of patients had cough 91.2% and sputum production 76.5%. Clinically, 41.2% of patients had previous history of TB 14-34, 38.2% had cardiac diseases 13-34, and 35.3% had diabetes mellitus 12-34. The most common CT findings in our study were nodular lesions 100% and bronchiectasis 85.29%. Regarding the severity, grade I bronchiectasis was the most prevalent. Other prominent findings were tree-in-bud sign 88.2%, consolidation 52.94%, and lobar fibrosis and volume loss 67.6%. There was no significant zonal distribution of findings. In conclusion, nodular lesions and bronchiectasis are the most frequent features in CT scan of M. simiae pulmonary infection.





Autor: Ayeh Baghizadeh, Payam Mehrian, and Poopak Farnia

Fuente: https://www.hindawi.com/



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