A randomized trial of preoperative oral carbohydrates in abdominal surgeryReport as inadecuate

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BMC Anesthesiology

, 14:93

Perioperative medicine and outcome


BackgroundCarbohydrate-rich liquid drinks CRLDs have been recommended to attenuate insulin resistance by shortening the preoperative fasting interval. The aim of our study the effect of preoperative oral administration of CRLDs on the well-being and clinical status of patients.

MethodsA randomized, double blind, prospective study of patients undergoing open colorectal operations CR and open cholecyctectomy CH was conducted. Patients were divided into three groups: study, placebo, and control. Visual analogue scale VAS scores for seven parameters thirst, hunger, anxiety, mouth dryness, nausea, weakness and sleep quality were recorded and compared for two different time periods up to 24 h postoperatively and from 36 to 48 h postoperatively. The Simplified Acute Physiology Score changes SAPS-II between the three groups were also studied.

ResultsThere were 142 patients American Society of Anesthesiology ASA I or II enrolled in the study CR = 71 and CH = 71. There were no significant differences in postoperative SAPS-II scores or lengths of hospital stay LOS between the groups. However, in CR patients, the degree of thirst was partially improved by drinking CRLDs P = 0.027. In CH patients, on the other hand, feelings of thirst, hunger, mouth dryness, nausea and weakness showed significant improvement P < 0.05.

ConclusionOral administration of carbohydrate-rich liquid drinks CRLDs improves the well-being in patients undergoing CH, but the effect is less evident in patients undergoing CR. No significant improvements were seen in clinical status or in length of hospital stay in either group.

Trial registrationANZCTR.org.au: ACTRN12614000995673 registered on 16-09-2014.

KeywordsCarbohydrates Fasting Thirst Preoperative use of carbohydrates Postoperative period Electronic supplementary materialThe online version of this article doi:10.1186-1471-2253-14-93 contains supplementary material, which is available to authorized users.

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Author: Fatos Sada - Avdyl Krasniqi - Astrit Hamza - Agreta Gecaj-Gashi - Besnik Bicaj - Floren Kavaja

Source: https://link.springer.com/

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