Serum levels of interleukin-6 are not dependent on the kidney functionReport as inadecuate

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Mediators of Inflammation - Volume 1 1992, Issue 3, Pages 197-199

Department of Medical Microbiology, Clinical Immunology, Lund University, Sölvegatan 23, Lund 223 62, Sweden

Copyright © 1992 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 IL-6 are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relation was found between serum levels of IL-6 and s-creatinine, r = 0.004. On the other hand, the serum concentration of complement protein factor D and soluble IL-2 receptor showed a good correlation to s-creatinine, r = 0.92 and 0.79, respectively. In conclusion, serum levels of IL-6 are not dependent upon a reduced kidney function.

Author: L. Nässberger



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